Placing your character in context. Where you put your character? It may seem obvious to you or you may not know where you want to make your character. Like the painting can be done either in harmony or contrast.
If you go with topics that may be natural harmony of the vampires to be in cemeteries or graves, or even next to a 18 th century by the bed raised. However, if you go for the hand you might want to do something different with your character. Putting them out of their norm can add impact or discord, which will make the viewer sit up and take note. You must be happy to do this but not like everyone will like and some people are immediately turned off the image. It seems that there are plenty of rules about what is acceptable for a vampire to do or where they are for what you have been warned! This does not mean they can not or should not explore alternatives, but only distance that can cause a storm of strong opinions.
For example, how do you feel about a vampire nun? Or a vampire on an alien planet? Or even the purchase of blood along with Mrs. Jones? Or if you were creating a werewolf. A werewolf is going to take a walk on a leash on a beautiful Sunday afternoon? Silly, perhaps, but outside the norm and can let their imagination and create better tracks of your characters. Of course, a more sinister theme that work best and have an equal or greater impact, but these examples are designed to shake up comfortable standard form of vampires in graveyards.
Another option is to limit the substance of stains and colors, this is the impact on their chosen creature or item, it is also easier to paint. This is like putting all focus on a photo. If the background is dark also shows their willingness to stand out even more. Have fun with it and see what works for you.